Spontaneous Bacterial Peritonitis

Diagnosis

  • Up to 10% are asymptomatic
  • > 250 PMNs/ml is diagnostic
  • Putting 20 ml of ascitic fluid in 2 separate culture bottles increases yield 25%
  • Each hour of delay in tx increases mortality 3%

Treatment

  • Ceftriaxone or cefotaxime
  • Albumin after paracentesis:
    • If creat > 1 mg/dl, BUN >30 mg/dl or total bili > 4 mg/dl
    • Dose is 1.5 gram/kg