e.g. > 5 days

DDx

• Kawasaki
• Malignancy
• Osteomyelitis
• Bartonella
• Bacteremia
• UTI
• MAS/HLH
• Rheum

Kawasaki Disease

• Clinical features:
  • Fever > 38 C x 5 d
  • Conjunctival injection (limbic sparing, non-exudative)
  • Rash: Polymorphous non-vesicular
  • Mucosal changes (lips and tongue)
  • Cervical LAD > 1.5 cm
  • Edema/desquamation palms/soles
• If all 5 clinical features present can dx after 4 days of fever
• Fever > 7 days in < 6 mo should be considered Kawasaki until proven otherwise