Cirrhosis Complications

SBP

  • Dx > 250 PMNs
  • Tx ceftriaxone 1 g or cefoxitin 2 g
  • Albumin 1.5 g/kg (that’s a high dose) if:
    • Creat >1
    • BUN >30
    • Bili > 4

Variceal Bleed

  • Massive transfusion
  • Fibrinogen
    • Target > 150 or
    • Empiric 10 units cryo (each unit is 10-15 ml and raises fibrinogen ~7)
  • Octreotide – 50. mcg bolus then drip
  • Ceftriaxone 1 g
  • MN Tube or Blakemore

Large Volume Paracentesis

  • 6-8 g/L of fluid removed for paracentesis of ≥4-5 L